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VOLUME 6 , ISSUE 1 ( January-June, 2021 ) > List of Articles

SYSTEMATIC REVIEW

Induced Periapical Bleeding in Regeneration of Immature Permanent Teeth with Necrosis: A Systematic Review

Ammar S Al Shamrani

Keywords : Immature permanent teeth, Necrosis pulp, Regenerative endodontic treatment, Systematic review

Citation Information : Al Shamrani AS. Induced Periapical Bleeding in Regeneration of Immature Permanent Teeth with Necrosis: A Systematic Review. Cons Dent Endod J 2021; 6 (1):6-13.

DOI: 10.5005/jp-journals-10048-0068

License: CC BY-NC 4.0

Published Online: 30-09-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Background and objectives: Regenerative treatment of immature teeth leads to continued root maturation thereby restores the physiologically functional pulp-dentin complex. The present systematic review is conducted to evaluate the efficacy of regenerative endodontic treatment by induced periapical bleeding (IPB) in the regeneration of immature necrosed permanent teeth with an open apex. Materials and methods: This review was conducted in adherence to PRISMA standards and was registered in PROSPERO with registration number CRD42018091574. We graded the methodological quality of the studies using Cochrane's tool of risk of bias in nonrandomized studies–of interventions (ROBINS-I). Results: In total, 200 studies were identified for screening, and nine studies were eligible. The quality assessment rated one study as strong, three studies (33.3%) as fair, and five studies (55.6%) as poor. The number of study participants ranged from 17 to 118 (total n = 394), with a mean of 43.8. Four studies showed 100% clinical success with IPB. The radiographic success ranged from 60 to 100%. Conclusion: All of the included studies showed IPB treatment resulted in increased root length, progressive thickening of the dentinal walls, and narrowing of the canal space. Induced periapical bleeding is the best treatment of choice for immature permanent teeth with pulpal necrosis.

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