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VOLUME 1 , ISSUE 2 ( July-December, 2016 ) > List of Articles


Healing of Large Periapical with Tricalcium Silicate-based Root End Filling Material

Snehal S Sonarkar, Rucheet Purba, Rajesh Podar

Keywords : Apicoectomy, Biodentine™, Endodontic microsurgery, Periradicular pathology, Periradicular surgery

Citation Information : Sonarkar SS, Purba R, Podar R. Healing of Large Periapical with Tricalcium Silicate-based Root End Filling Material. Cons Dent Endod J 2016; 1 (2):41-45.

DOI: 10.5005/jp-journals-10048-0011

License: CC BY-NC 4.0

Published Online: 01-11-2018

Copyright Statement:  Copyright © 2016; The Author(s).


Periradicular disease is mainly caused by varied microflora present in the root canal system. These microorganisms are removed to some extent with the help of various steps in root canal treatment. The infected teeth are treated nonsurgically rather than treating directly by surgical root canal treatment. For the successful surgical treatment, root end filling material is placed at the root end. This case report describes a case which is prior to nonsurgical method; however, because of complications these teeth are treated surgically. Biodentine being a biocompatible material can be used as a root end filling material, according to the manufacturer's instructions. The patient was recalled at a regular interval and it was found that periradicular tissue responded well to the restorative material. However, the long-term success rate for this material is yet to be evaluated, so for evaluation this case is followed up.

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  1. Johnson BR, Fayad MI, Witherspoon DE. Chapter 11. Periradicular surgery. In: Hargreaves KM, Cohen S, editors. Cohen's pathways of the pulp. 10th ed. St. Louis (MO): Mosby; 2011; p. 721-722.
  2. Hermann BW. On the reaction of the dental pulp to vital amputation and calxyl capping. Dtsch Zahnarztl Z 1952 Dec;7(24):1446-1447.
  3. Torabinejad M, Hong CU, McDonald F, Pitt Ford TR. Physical and chemical properties of a new root-end filling material. J Endod 1995 Jul;21(7):349-353.
  4. Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endod 1999 Mar;25(3):197-205.
  5. Biodentine™ – Publications and Communications 2005-2010. Research & Development Septodont, Paris; 2010 [accessed 2014 Nov 26].
  6. Valimaki VV, Aro HT. Molecular basis for action of bioactive glasses as bone graft substitute. Scand J Surg 2006;95(2): 95-102.
  7. Yuan Z, Peng B, Jiang H, Bian Z, Yan P. Effect of bioaggregate on mineral-associated gene expression in osteoblast cells. J Endod 2010 Jul;36(7):1145-1148.
  8. Park JW, Hong SH, Kim JH, Lee SJ, Shin SJ. X-Ray diffraction analysis of white ProRoot MTA and Diadent BioAggregate. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jan;109(1):155-158.
  9. Han L, Okiji T. Uptake of calcium and silicon released from calcium silicate-based endodontic materials into root canal dentin. Int Endod J 2011 Dec;44(12):1081-1087.
  10. Laurent P, Camps J, About I. Biodentine™ induces TGF-β1 release from human pulp cells and early dental pulp mineralization. Int Endod J 2012 May;45(5):439-448.
  11. Koubi S, Elmerini H, Koubi G, Tassery H, Camps J. Quantitative evaluation by glucose diffusion of microleakage in aged calcium silicate-based open-sandwich restorations. Int J Dent 2012;2012:105863.
  12. Zhou HM, Shen Y, Wang ZJ, Li L, Zheng YF, Hakkinen L, Haapasalo M. In vitro cytotoxicity evaluation of a novel root repair material. J Endod 2013 Apr;39(4):478-483.
  13. Perard M, Le Clerc J, Watrin T, Meary F, Perez F, Tricot-Doleux S, Pellen-Mussi P. Spheroid model study comparing the biocompatibility of Biodentine and MTA. J Mater Sci Mater Med 2013 Jun;24(6):1527-1534.
  14. Luo Z, Li D, Kohli MR, Yu Q, Kim S, He WX. Effect of Biodentine on the proliferation, migration and adhesion of human dental pulp stem cells. J Dent 2014 Apr 17;42(4):490-497.
  15. Raju VG, Venumbaka NR, Mungara J, Vijayakumar P, Rajendran S, Elangovan A. Comparative evaluation of shear bond strength and microleakage of tricalcium silicate-based restorative material and radioopaque posterior glass ionomer restorative cement in primary and permanent teeth: an in vitro study. J Indian Soc Pedod Prev Dent 2014 Oct-Nov;32(4):304-310.
  16. Malkondu Ö, Karapinar Kazandað M, Kazazoðlu E. A review on biodentine, a contemporary dentin replacement and repair material. Biomed Res Int 2014;2014:160951.
  17. About I 2009 Effects des matériaux bioactifs Biodentine™ et Calcipulpe® sur les étapes précoces de la régénération dentinaire. Report RD RA DEV 94-013. From Biodentine™- Publications and Communications 2005–2010. Research & Development Septodont, Paris; 2010.
  18. Kim S, Kratchman S. Modern endodontic surgery concepts and practice: a review. J Endod 2006 Jul;32(7):601-623.
  19. Baumgartner JC, Siqueira JF Jr, Sedgley KM, Kishen A. Microbiology of endodontic disease. In. Ingle JI, Bakland LK, Baumgartner JC, editors. Ingles endodontics. 6th ed. Hamilton (ON): BC Decker Inc; 2008. p. 283.
  20. Chandra BS, Krishna VG. Endodontic surgery. In: Chandra BS, Krishna VG. Grossmans endodontic practice. 12th ed. Wolters Kluwer Health (India); 2010. p. 419.
  21. Del Fabbro M, Taschieri S, Testori T, Francetti L, Weinstein RL. Surgical versus non-surgical endodontic retreatment for periradicular lesions. Cochrane Database Syst Rev 2007 Jul;18(3):CD005511.
  22. Elemam FR, Pretty I. Comparison of the success rate of endodontic treatment and implant treatment. ISRN Dent 2011;2011:640509.
  23. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review – Part I: Chemical, physical and antibacterial properties. J Endod 2010 Jan;36(1):16-27.
  24. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review – Part III: clinical applications, drawbacks, and mechanism of action. J Endod 2010 Mar;36(3):400-413.
  25. Seok-Woo Chang. Chemical characteristics of mineral trioxide aggregate and its hydration reaction. Restor Dent Endod 2012 Nov;37(4):188-193.
  26. Pawar AM, Kokate SR, Shah RA. Management of a large periapical lesion using Biodentine™ as retrograde restoration with eighteen months evident follow up. J Conserv Dent 2013 Nov-Dec;16(6):573-575.
  27. Ravichandra PV, Vemisetty H, Deepthi K, Reddy SJ, Ramkiran D, Krishna MJN, Malathi G. Comparative evaluation of marginal adaptation of Biodentine™ and other commonly used root end filling materials – an in vitro study. J Clin Diagn Res 2014 Mar;8(3):243-245.
  28. Soudappan S, Sundaramurthy JL, Raghu S, Natanasabapathy V. Biodentine versus mineral trioxide aggregate versus intermediate restorative material for retrograde root end filling: an in vitro study. J Dent (Tehran) 2014 Mar;11(2): 143-149.
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